Ibuprofen and Infertility in Men Linked by Study

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This is a problem, as the function of LH is to stimulate the production of testosterone, and not to significantly surpass testosterone levels.

However, Kristensen emphasises that despite the results of the study, men should not stop taking the drug.

Within 14 days, testosterone-producing hormones in the men taking ibuprofen dropped, causing compensated hypogonadism, according to USA Today .

In the latest research, scientists looked at the impact of ibuprofen on 31 healthy young men over six weeks and performed further tests on cells and pieces of human testes in the lab. Ibuprofen lowered testosterone production in the tissues, but levels of the hormone remained the same in the men.

While this effect wasn't permanent, the researchers warned that prolonged use of ibuprofen by men could lead to low testosterone production - which might end up harming their fertility. In 2017, the NSAID that goes by brand names including Motrin and Advil raises the risk of heart attacks. A control group of 17 men took a placebo instead.

The small study, which was published yesterday (Jan. 8) in the journal Proceedings of the National Academy of Sciences, found that men who took 1,200 milligrams of ibuprofen a day for six weeks developed a hormonal condition that is linked with reproductive problems.

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'Several studies have shown mild analgesics exposure during foetal life is associated with anti-androgenic effects and congenital malformations.

Before now, he says, "most warnings regarding this family of painkillers have focused on limiting long-term use in the elderly to prevent gastrointestinal, renal and cardiac adverse effects".

"However, this is now speculative".

The good news is that the problems required multiple weeks of constant ibuprofen use, so there's no indication that handling the odd muscle ache or hangover with ibuprofen will cause problems.

Those in the ibuprofen group were given two doses of ibuprofen a day. It is worth noting that the study is actually a continuation of research looking into the effects of pain relievers on pregnant women.

William Colledge, professor of reproductive physiology at the University of Cambridge, who was not involved in the research, said: "It's a fascinating study that suggests that men should be cautious about using high doses of ibuprofen for extended periods".

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