Australia's Caleb Ewan (Orica-Scott) was second over the line with Germany's Andre Greipel (Lotto-Soudal) third. I gave all I had.
"Both days we have had a pretty solid head wind and also the roads here are quite dead so I think it's a combination of those two things that is making the racing slow".
With over 4,000 vertical metres of climbing, the race's second stage was animated by an early attack as six riders - Daniel Teklehaimanot (Dimension Data), Lukasz Owsian (CCC Sprandi Polkowice), Ilia Koshevoy (Wilier Triestina), Evgeny Shalunov (Gazprom - Rusvelo) and Simone Andreetta (Bardiani CSF) - broke clear after just six kilometres.
The bunch swept up Bialoblocki at the summit, 46 seconds down on the escapees, with 21K remaining. "Giacomo Nizzolo (Italy / Trek) +10" 6.
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He was followed across the line by Italy's Roberto Ferrari and Belgium's Jasper Stuyven, with Colombia's Fernando Gaviria coming fourth.
The 30-year-old Pirazzi won the mountains classification in 2013 and a stage the following year in the first of the three Grand Tours. Bora-Hansgrohe's Austrian will wear the 100th Giro's first pink jersey after fending off the sprinters.
Greipel now has 22 victories from Grand Tours including 11 from the Tour de France and four from the Tour of Spain.
Bahrain-Merida did much of the heavy lifting at the front from that point, but in the final kilometre it was Greipel who took centre stage to claim the seventh Giro stage win of his career. Daniel Teklehaimanot (Dimension Data): 72pts 3. "Through the city the lead-out trains, I don't know, they lost my wheel or something and I had a gap", Postlberger, who even had time to raise his arms in celebration before the finish, said. An, er, proud Andre Greipel after making a little piece of history on Saturday.